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Updated: 08 Oct 2025

10 Best Beauty Drugstore Setting Spray

#1
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NYX PROFESSIONAL MAKEUP Butter Gloss, Non-Sticky Lip Gloss - Strawberry Cheesecake (Warm Pink)

Brand: NYX Professional Makeup
$18.97
⭐ 4.7
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    Butter Gloss: Buttery soft and silky smooth, our decadent Butter Gloss is available in a wide variety of sumptuous shades; Each glossy color delivers sheer to medium coverage that melts onto your lips
  • Kissable Lips: Our best selling Butter Gloss goes on smooth and creamy and is never sticky, leaving your lips soft, supple and kissable; Try all of our delicious shades, from Angel Food Cake to Tiramisu
  • Lip Products for the Perfect Pout: Doll your lips in creamy, long lasting perfection; Try our complete line of lip makeup including liquid lipstick, lip gloss, lip cream, lip liner and butter gloss
  • Cruelty Free Cosmetics: We believe animals belong in our arms, not in a lab; All of our makeup is certified and acknowledged by PETA as a cruelty free brand; We don't test any of our products on animals
  • Discover NYX Professional Makeup: Try all of our professional makeup products today from eyeshadow, eyeliner, and false lashes to liquid lipstick, lip gloss, primer, concealer, setting sprays and eyebrow makeup
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#2
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Urban Decay All Nighter Long Lasting Makeup Setting Spray 118ml

Brand: URBAN DECAY
$68.99
⭐ 4.1
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    #1 FOR A REASON - Our award-winning, natural finish setting spray ensures your makeup stays vibrant and flawless for up to 16 hours, thanks to its advanced temperature control technology that prevents makeup meltdowns.
  • BENEFITS - Waterproof, smudge-proof, and transfer-resistant. This makeup fixing spray applies evenly with a super-fine mist for smoother-looking skin and more vibrant makeup. The lightweight formula is breathable and comfortable, providing a moisturizing feel without leaving your skin feeling tight or dry.
  • THE RESULT - Offers a natural, real-skin finish that blends makeup into skin for a blurred, soft focus effect, making skin appear smoother and pores more refined.
  • FEATURES - This paraben-free setting spray actually lowers makeup temperature. The temperature control technology has time-released molecules that burst gradually and helps keep the face feeling cooled and refreshed while preventing flaking or creasing into fine lines.
  • HOW TO USE - Shake after completing your makeup look. Hold bottle 8-10 inches away from your face. Spray in an "X" & "T" formation 2-4 times. Use to set your cream/liquid foundations, face powder, blush, contour, eyeshadow, eyeliner, mascara, and lip looks.
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#3
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Milani Make It Last Matte Charcoal Setting Spray - Cruelty-Free Makeup Primer for Oily Skin - Long Lasting Matte Finish (2.03 Fl. Oz.)

Brand: Milani
$27.09
⭐ 4.7
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    PRIME + CORRECT + SET: Make It Last Charcoal Matte Setting Spray preps your face, features micro-fine charcoal powder and silica to set makeup. It reduces the appearance of imperfections and then locks in for the long haul. Sets and mattifies skin for up to 16 hours without a crease or smudge in sight. Spray before or after makeup application, or wear it alone for a captivating natural finish.
  • LONG-LASTING WEAR: This illuminating finishing spray and makeup primer delivers just the right dose of dewy to your complexion with a cooling, refreshing feeling, while locking in your makeup for up to 16 hours without creasing, smudging or fading!
  • VEGAN, CRUELTY-FREE BEAUTY: The vegan formula primes, hydrates, and illuminates your skin. Spray under or over makeup to set your look, or wear on its own for a healthy radiance all day long.
  • TIPS & TRICKS: Hold bottle 8-10 inches away from your face and spray in a zigzag formation. Do not spray directly into eyes.
  • WE ARE MILANI: Born in East LA, we've always been connected to the rich diversity of our neighborhood, because its a place that truly embodies the melting pot of Los Angeles. We're not inspired by couture and top models. Our passion is real people, living real lives. Beauty is for everyone. No matter who you are or where you come from, we're here to fuel your self-expression with makeup for every shade, attitude, and ethnicity. No judgment. No exceptions.
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