Advertising Disclosure
Updated: 06 Apr 2026

10 Best Cold Sore Treatments Docosanol

#1 Best Pick
Dermal Therapy Cold Sore Lysine Plus Gel 5 g

Dermal Therapy Cold Sore Lysine Plus Gel 5 g

Brand: Dermal Therapy
Read more
  • Contains lysine, propolis and lemon balm to provide fast effect
  • Specifically designed to relieve cold sore symptoms
  • Clear gel formulation for discreet application
  • Provides targeted relief and soothing effects
Check latest price on Amazon
#2 Best Value
Healthy Care Super Lysine Cold Sore Relief Tablets - Reduce Symptoms of Cold Sores & Promotes Immune Function - Supports Skin Health - Premium Quality Dietary Supplement - 100 Tablets - 1000 mg

Healthy Care Super Lysine Cold Sore Relief Tablets - Reduce Symptoms of Cold Sores & Promotes Immune Function - Supports Skin Health - Premium Quality Dietary Supplement - 100 Tablets - 1000 mg

Brand: Healthy Care
Read more
  • The information below is per-pack only
  • Rapid relief: Healthy Care super lysine cold sore relief is specifically formulated with a high-strength dose of lysine, an essential amino acid, to effectively manage and reduce the symptoms of facial cold sores. Enhanced with vitamin C and zinc, this supplement is designed to strengthen immune defences and skin health.
  • Health benefits: This lysine supplement not only aims to lessen the severity and occurrence of cold sores but also supports collagen production for skin health and accelerates wound healing. The added zinc promotes robust immune function, and the antioxidant properties of vitamin C help reduce oxidative pressure.
  • Convenient tablet form: The product is conveniently packaged in tablet form, making it easy to consume on a daily basis. Each tablet is crafted to be easy to swallow and is formulated without added sugars, yeast, lactose, gluten, salt, or any artificial colours and flavours, catering to a wide range of dietary needs and preferences.
  • Clean and pure: Free from added sugar, yeast, gluten, salt, artificial colours, and preservatives, these lysine tablets are an excellent choice for individuals looking for a pure supplement option. This commitment to purity makes them suitable for a wide range of dietary preferences and sensitivities.
Check latest price on Amazon
#3 Budget Pick
Nyal Antiviral Cold Sore Cream 5 g

Nyal Antiviral Cold Sore Cream 5 g

Brand: Nyal
Read more
  • Helps fight the virus to speed healing
  • Highly effective on itching, burning or tingling
  • Can help accelerate the healing process
  • Country of Origin: Australia
Check latest price on Amazon
#4 Top Choice
Blackmores Lyp-sine | Relieves Symptoms of Facial Cold Sores| Supports Immune System Health| 30 Tablets

Blackmores Lyp-sine | Relieves Symptoms of Facial Cold Sores| Supports Immune System Health| 30 Tablets

Brand: Blackmores
Read more
  • Blackmores Lyp-Sine is a dose of the amino acid lysine, which can help reduce the number of outbreaks of cold sores, helps relieve symptoms and helps reduce healing time of lesions
  • Contains vitamin C and zinc to promote healing of lesions
  • Blackmores ensure testing of the quality of our products to ensure high quality goes into our bottles
  • Blackmores is Australia’s most trusted vitamin and supplement brand as voted by Australians in the 2009-2017 Readers Digest Most Trusted Survey
Check latest price on Amazon
#5 Popular Choice
Pharmacy Action Cold Sore Cream 5g (Generic for Zovirax)

Pharmacy Action Cold Sore Cream 5g (Generic for Zovirax)

Brand: PHARMACY ACTION
Read more
Check latest price on Amazon
#6 Top Pick
Healthy Care Super Lysine Cold Sore Relief Tablets - Reduce Symptoms of Cold Sores & Promotes Immune Function - Supports Skin Health - Premium Quality Dietary Supplement - 100 Tablets - 1000 mg

Healthy Care Super Lysine Cold Sore Relief Tablets - Reduce Symptoms of Cold Sores & Promotes Immune Function - Supports Skin Health - Premium Quality Dietary Supplement - 100 Tablets - 1000 mg

Brand: Healthy Care
Read more
  • Rapid relief: Healthy Care super lysine cold sore relief is specifically formulated with a high-strength dose of lysine, an essential amino acid, to effectively manage and reduce the symptoms of facial cold sores. Enhanced with vitamin C and zinc, this supplement is designed to strengthen immune defences and skin health.
  • Health benefits: This lysine supplement not only aims to lessen the severity and occurrence of cold sores but also supports collagen production for skin health and accelerates wound healing. The added zinc promotes robust immune function, and the antioxidant properties of vitamin C help reduce oxidative pressure.
  • Convenient tablet form: The product is conveniently packaged in tablet form, making it easy to consume on a daily basis. Each tablet is crafted to be easy to swallow and is formulated without added sugars, yeast, lactose, gluten, salt, or any artificial colours and flavours, catering to a wide range of dietary needs and preferences.
  • Clean and pure: Free from added sugar, yeast, gluten, salt, artificial colours, and preservatives, these lysine tablets are an excellent choice for individuals looking for a pure supplement option. This commitment to purity makes them suitable for a wide range of dietary preferences and sensitivities.
  • Quality first: Australia is one of the few countries in the world that regulates health supplements with therapeutic regulations. Before anything leaves our warehouse it has to go through over 20 quality checks. All conforming to the TGA and cGMP standards.
Check latest price on Amazon
#7 Top Pick
Betadine Cold Sore Ointment, Treatment of Cold Sores, 7.5g

Betadine Cold Sore Ointment, Treatment of Cold Sores, 7.5g

Brand: Betadine
Read more
  • Betadine Cold Sore Ointment is recommended to help with the treatment of cold sores
  • If applied at the first signs of a cold sore (usually a tingling or itching sensation), this ointment can help to slow the progress of infection
  • Cold Sore Ointment can help reduce the risk of spreading the infection
  • The convenient tube makes the ointment easy to apply
  • Always read the label; Follow the directions for use; If symptoms persist, talk to your health professional; Betadine is a registered trademark of Mundipharma AG, used under license
Check latest price on Amazon
#8 Top Pick
Compeed Cold Sore Discreet Healing Patch, 15 Patches, Cold Sore Treatment, More Convenient than Cold Sore Creams, Dimensions: 1.5cmx1.5cm

Compeed Cold Sore Discreet Healing Patch, 15 Patches, Cold Sore Treatment, More Convenient than Cold Sore Creams, Dimensions: 1.5cmx1.5cm

Brand: Compeed
Read more
  • FAST HEALING: ultra-thin hydrocolloid gel provides a moist environment to help reduce scab formation
  • ACT LIKE A SHIELD: provides a protective barrier against external environment, helping to reduce the risk of contamination
  • STAYS IN PLACE UP TO 12 HOURS AND DISCREET: adhesive, tapered edges so Compeed flexes with movement, and translucent patch blends in with the skin
  • STARTS TO WORK from the very first sign and continues throughout all stages
  • NEW APPLICATOR : to improve ease of application. Tip: try not to press on circular section of green tab when preparing to apply
Check latest price on Amazon
#9 Top Pick
Zovirax Antiviral Cold Sore Treatment Cream Tube, 2g | Aciclovir 5% w/w

Zovirax Antiviral Cold Sore Treatment Cream Tube, 2g | Aciclovir 5% w/w

Brand: Zovirax
Read more
  • Contains the anti-viral agent, aciclovir 5 percent, that inhibits the multiplication of the cold sore virus
  • Zovirax MAC-P penetrating formula gets to the site of infection to speed healing and get rid of cold sores
  • Available in a tube or pump for a clean, controlled application
  • Easy rub-in formula: with dimethicone that disappears quickly into the skin
  • Cuts healing time in half compared with no cold sore treatment (On average: compared with historical data for untreated cold sores)
Check latest price on Amazon

More products you might like!!