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Updated: 21 May 2026

10 Best Computer Mice Vertical

#1 Best Pick
Perixx PERIMICE-513 Wired Vertical USB Mouse - 6 Buttons with 1000/1600 DPI - Right-Handed Design - Black

Perixx PERIMICE-513 Wired Vertical USB Mouse - 6 Buttons with 1000/1600 DPI - Right-Handed Design - Black

Brand: Perixx
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  • ERGONOMIC DESIGN - A right-handed vertical mouse that promotes a natural handshake position while using to prevent twisting the forearm while using and reduce muscular strain and repetitive strain injuries (RSI)
  • ADJUSTABLE TRACKING DPI - High precision optical sensor that can be adjusted with 1000/1600 DPI resolution
  • DURABLE MATERIAL - High-quality rubber-coating surface that gives a nice grip to hold for long hours of use; Dimensions: 4.92 x 2.44 x 3.03 in (125 x 62 x 77 mm); Weight: 0.35 lb (160 g)
  • EASY AND RELIABLE CONNECTION - Plug and play setup with 6-ft (1.8 m) cord for flexible setup condition to reach even PC under the desk; No extra driver required
  • COMPATIBILITY - Windows 7, 8, 10, 11, and later versions; weights 0.35 lb (15 kg), cable is 5'9 ft (1.8 m)
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#2 Best Value
ProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz USB-A Optical Mice for Windows, Mac OS, Pink

ProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz USB-A Optical Mice for Windows, Mac OS, Pink

Brand: ProtoArc
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  • Connection Guide: This mouse pairs via Bluetooth or the included USB-A receiver only. Note: A USB-C receiver is not included. The Type-C cable is for charging
  • Connect up to 3 Devices: This ergonomic wireless mouse features dual BT 5.0 and 2.4G USB-A connectivity modes for simultaneous connection of up to 3 different devices, and is compatible with Windows 8, Windows 10 or higher, Mac OS X 10.12 or higher, and Android 4.3 or higher
  • Rechargeable Ergonomic Mouse: The Bluetooth Vertical Mouse has a built-in 500mAh Li-Ion battery that can be conveniently recharged using the included Type-C cable(The Type-C cable is for charging only)
  • Ergonomic Vertical Design: The ergonomic mouse wireless keeps your wrist naturally straight, putting your forearm and wrist in a more natural and relaxed position, which can reduce discomfort and strain, helping to improve productivity and reduce the risk of repetitive strain injuries compared to a standard mouse. Warm tips: We encourage you to relax your palm and hold the mouse naturally when using a vertical mouse
  • Perfect Fit for Small to Medium Hands: Designed specifically for hand lengths under 7.5 inches (19.05 cm), the EM11 NL reduces wrist strain by aligning with your natural grip. Please measure the size before ordering for a better fit and more comfort
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#3 Budget Pick
Wired Mouse,SUIJIEEN Ergonomic Mouse 6 Buttons Silent Mouse 4 Adjustable DPI Vertical Mouse Compatible with Windows/Chrome/Laptop/Computer

Wired Mouse,SUIJIEEN Ergonomic Mouse 6 Buttons Silent Mouse 4 Adjustable DPI Vertical Mouse Compatible with Windows/Chrome/Laptop/Computer

Brand: SUIJIEEN
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  • ERGONOMIC DESIGN - Places your hand in a natural "handshake" wrist & arm position for smoother movement and less muscle tension. Cute Rounded shape just fits in the palm of your hand. Once you get used to it, you will love it!
  • ERGONOMIC DESIGN - Places your hand in a natural "handshake" wrist & arm position for smoother movement and less muscle tension. Cute Rounded shape just fits in the palm of your hand. Once you get used to it, you will love it!
  • EASIER WEB BROWSING - Advanced "Back" & "Forward" functionality buttons that located near the thumb area will provide convenience when web page browsing. *For Mac series, Forward / Backward buttons will not work.
  • WIDE COMPATIBILITY - Compatible with most system including Windows 11 / 10 / 8.1 / 8; macOS (Sonoma)14, (Ventura) 13, (Monterey) 12, (BigSur) 11, macOS 10.12~10.15; Chrome OS and versions later on. Fit for Notebook, PC, Laptop, Computer and other device. *Not fully compatible with Apple products.
  • PLUG AND PLAY - No driver required. ※Notice: All SANWA Products provide the same high quality after-service as in Japan, including a 1-Year Worry-Free Manufacturer Warranty & free lifetime technical support.※
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#4 Top Choice
Logitech MX Vertical Advanced Ergonomic Wireless Mouse, Graphite

Logitech MX Vertical Advanced Ergonomic Wireless Mouse, Graphite

Brand: Logitech
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  • Ergonomic design with a 57° vertical angle to reduce wrist strain
  • High-precision 4000 DPI sensor for 4x less hand movement
  • Connect via Logitech Unifying receiver, Bluetooth, or USB-C cable
  • Seamlessly switch between up to 3 devices with Easy-Switch technology
  • Compatible with multiple operating systems including Windows, macOS, and Linux
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#5 Popular Choice
Wireless Rechargeable Ergonomic Mouse, 2.4G Small Wireless Vertical Optical Mice with 3 Adjustable DPI Levels for Laptop, PC, Computer, Desktop, Notebook

Wireless Rechargeable Ergonomic Mouse, 2.4G Small Wireless Vertical Optical Mice with 3 Adjustable DPI Levels for Laptop, PC, Computer, Desktop, Notebook

Brand: shoplease
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  • 【Rechargeable Battery】-- Built-in rechargeable battery. You no longer need to buy batteries, very convenient !! EASY TO USE -- One USB receiver at the bottom of the mouse, Just Plug and Play!
  • 【Ergonomic Design】-Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
  • 【More Adjustment】-800 / 1200 / 2000 / 3200 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
  • 【Useful Page Buttons】-Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
  • 【Wide compatibility】-Compatible with Windows 7/8/10 / Vista / XP / 2000, Mac OS, Linux (NOTE: the forward and backward buttons are not recognized on Mac). Plug and play.
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#6 Top Pick
Wireless Vertical Mouse,SUIJIEEN Ergonomic Mouse 2.4GHz Optical Carpal Tunnel Mouse 6 Buttons Wireless Mouse for Laptop Desktop PC

Wireless Vertical Mouse,SUIJIEEN Ergonomic Mouse 2.4GHz Optical Carpal Tunnel Mouse 6 Buttons Wireless Mouse for Laptop Desktop PC

Brand: SUIJIEEN
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  • Ergo-Excellence: Relieve hand pain and cramping with our ergonomically crafted vertical mouse. Precision shaping, side grips, thumb rest, and strategic buttons ensure a stylish and comfortable computing experience.
  • High-Precision Mouse Control: Your new best friend for exact mouse movements! This ergonomic mouse features a 2400 DPI optical sensor, offering seamless tracking on any surface. Adapt to your needs with resolutions of 1000DPI, 1600DPI, 2000DPI, or 2400DPI.
  • Efficiency in Every Click: Streamline web browsing with Backward/Forward Page buttons. Positioned above the thumb rest, a light thumb press effortlessly navigates pages, preventing wrist strain during prolonged use.
  • Wireless Flexibility: Go cord-free with a 2.4 GHz connection and a 49-foot range. Simply plug in the USB receiver and enjoy a clutter-free workspace with no delays or dropouts, maximizing your productivity from any spot.
  • Whisper Quiet, Maximum Focus: Minimize disruptive clicks with advanced stability. Work in a noise-free environment with the vertical mouse, enhancing concentration, learning, and productivity.
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#7 Top Pick
UGREEN Vertical Ergonomic Mouse, Bluetooth & 2.4G, Silent Quiet Clicks, 5 Buttons, 4000 DPI & 4 Adjustable DPI, for Laptop, Mac, Chromebook, PC, Windows, Black

UGREEN Vertical Ergonomic Mouse, Bluetooth & 2.4G, Silent Quiet Clicks, 5 Buttons, 4000 DPI & 4 Adjustable DPI, for Laptop, Mac, Chromebook, PC, Windows, Black

Brand: UGREEN
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  • Ergonomic Design: UGREEN vertical mouse is designed with an ergonomic shape that contours the natural curvature of your hand, providing a comfortable and fatigue-free grip.
  • 57° Vertical Angle: The mouse features a precisely angled 57° vertical design, optimized for natural and comfortable hand positioning. This angle not only reduces wrist strain but also aligns your hand and wrist in a more relaxed position.
  • Dual Connectivity with Bluetooth and 2.4G: The mouse offers both Bluetooth and 2.4G wireless connections, giving you the flexibility to pair with multiple devices simultaneously. The Bluetooth connection ensures secure and stable connectivity within a range of up to 10 meters, providing seamless performance even in busy environments.
  • High DPI and Adjustable Levels: Our mouse offers a high DPI range with four adjustable levels: 1000, 1600, 2000, and 4000. This provides exceptional precision and control for both desktop and gaming applications.
  • Compatibility and Flexibility: UGREEN vertical mouse is designed with widespread compatibility in mind. It works seamlessly with both Mac and Windows systems, as well as various operating systems and devices. This flexibility ensures that our mouse can fit into any user's workflow and personal preferences. Note: Ubuntu and Mac systems do not support the middle button scroll wheel function.
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#8 Top Pick
ProtoArc Ergonomic Vertical Mouse, EM11 NL Bluetooth Rechargeable Mouse Wireless, Ergo Mouse with 3 Multi-Device for PC/Notebook/Laptop, 2.4GHz Optical Mouse for Windows, Mac OS Black

ProtoArc Ergonomic Vertical Mouse, EM11 NL Bluetooth Rechargeable Mouse Wireless, Ergo Mouse with 3 Multi-Device for PC/Notebook/Laptop, 2.4GHz Optical Mouse for Windows, Mac OS Black

Brand: ProtoArc
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  • Connect up to 3 Devices: This ergonomic wireless mouse features dual BT 5.0 and 2.4G USB connectivity modes for simultaneous connection of up to 3 different devices, and is compatible with Windows 8, Windows 10 or higher, Mac OS X 10.12 or higher, and Android 4.3 or higher
  • Rechargeable Ergonomic Mouse: The Bluetooth Vertical Mouse has a built-in 500mAh Li-Ion battery that can be conveniently recharged using the included Type-C cable
  • Ergonomic Vertical Design: The ergonomic mouse wireless keeps your wrist naturally straight, putting your forearm and wrist in a more natural and relaxed position, which can reduce overall fatigue compared to a standard mouse. Warm tips: We encourage you to relax your palm and hold the mouse naturally when using a vertical mouse
  • Warm tips: Since it takes a learning curve to get used to the shape when using our ergonomic mouse for the first time, it may cause inconvenience to your mouse grip, We recommend that you take 1-2 weeks to get used to it, as many users find that it will help reduce the pressure and pain on your wrist caused by long-term use of the mouse and improve comfort
  • Notes: We recommend that small to medium hands use our ergonomic vertical mouse. Please measure the size before ordering for a better fit and more comfort
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#9 Top Pick
Wireless Vertical Mouse, 2.4G Wireless Ergonomic Optical Mouse with 3 Adjustable 800/1200 /1600 DPI, 6 Buttons Compatible Laptop, PC, Computer, Desktop, Notebook

Wireless Vertical Mouse, 2.4G Wireless Ergonomic Optical Mouse with 3 Adjustable 800/1200 /1600 DPI, 6 Buttons Compatible Laptop, PC, Computer, Desktop, Notebook

Brand: shoplease
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  • 【Ergonomic Design】-Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain
  • 【More Adjustment】-800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
  • 【Useful Page Buttons】-Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
  • 【Smart Dormancy】-Enters power saving mode (power is cut off completely) after 8 minutes idle, Press right or left button for it to wake.
  • 【Wide Compatibility】-Compatible with Windows 8/7/10 / Vista / XP / 2000, Mac OS, Linux (NOTE: the forward and backward buttons are not recognized on Mac). Plug and play.
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#10 Top Pick
Logitech Lift Vertical Ergonomic Wireless Mouse, Graphite

Logitech Lift Vertical Ergonomic Wireless Mouse, Graphite

Brand: Logitech
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  • Connect seamlessly via Bluetooth Low Energy or the included Logi Bolt USB receiver
  • Its 57 degree vertical angle promotes a natural handshake position
  • textured grip and snug thumb rest for level-above cosiness
  • Designed for small to medium sized hands
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