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Updated: 06 Apr 2026

10 Best Decongestant Sprays

#1 Best Pick
Difflam Plus Sore Throat Spray 30 ml, Watermelon

Difflam Plus Sore Throat Spray 30 ml, Watermelon

Brand: Difflam
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  • Spray has a triple action antibacterial + anti-inflammatory + anaesthetic formula
  • Fast relief of painful inflamed sore throats
  • Sugar free, lactose free, gluten free
  • Relieves symptoms of mouth ulcers, swelling, redness etc
  • Easy to use and carry in bag
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#2 Best Value
Sudafed Xylo Nasal Decongestant Spray, 20 count, Pack of 20

Sudafed Xylo Nasal Decongestant Spray, 20 count, Pack of 20

Brand: Sudafed
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  • Unblocks your nose
  • Clears congested sinuses
  • Moisturizes dry nasal lining
  • Get fast effective sinus relief
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#3 Budget Pick
Afrin No Drip 12-Hour Pump Mist, Severe Congestion - 2 pumps each 2/3 oz - Total 1.33 oz

Afrin No Drip 12-Hour Pump Mist, Severe Congestion - 2 pumps each 2/3 oz - Total 1.33 oz

Brand: Afrin
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  • Won't drip from nose or down throat.
  • Fast, Powerful Congestion Relief.
  • Maximum Strength.
  • Unique Formula with Menthol.
  • Afrin - Number One Brand in Doctor and Pharmacist Recommendations
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#4 Top Choice
ApoHealth Decongestant Nasal Spray 20ml

ApoHealth Decongestant Nasal Spray 20ml

Brand: APH
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#5 Popular Choice
Vicks Nasal Decongestant Inhaler Twin Pack

Vicks Nasal Decongestant Inhaler Twin Pack

Brand: Vicks
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  • Blocked nose relief anytime, anywhere
  • Help make the breathing clear and cool
  • Effectively provides quick relief from nasal congestion
  • Easy to use; Just inhale refreshing vapors through each nostril use as often as needed
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#6 Top Pick
Sudafed Nasal Decongestant Spray 2 x 20mL

Sudafed Nasal Decongestant Spray 2 x 20mL

Brand: Sudafed
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  • Sudafed Nasal Decongestant Spray 2 x 20mL
  • Product Type: MEDICATION
  • Brand: Sudafed
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#7 Top Pick
Demazin 12 Hour Nasal Decongestant 20ml

Demazin 12 Hour Nasal Decongestant 20ml

Brand: Demazin
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  • Demazin 12 Hour Nasal Decongestant 20ml
  • Product Type: MEDICATION
  • Brand: Demazin
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#8 Top Pick
Otrivin Menthol Nasal Spray, 10ml | Clears Blocked Noses Fast, Long Lasting Relief

Otrivin Menthol Nasal Spray, 10ml | Clears Blocked Noses Fast, Long Lasting Relief

Brand: Otrivin
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  • Starts unblocking the nasal airways within 5 minutes
  • Provides up to 10 hours of relief from nasal congestionEccles, R. et al. 2008. The nasal decongestant effect of xylometazoline in the common cold. An J of Rhyno1 22, 491496, 2008.
  • Added freshness of Menthol
  • Facilitates aid in case of swollen blood vessels
  • Relief of a blocked or runny nose caused by cold, flu, sinusitis, hay fever and more
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#9 Top Pick
Chemist Own Chemists Own Decongestant Nasal Spray 18Ml Generic Of Drixine

Chemist Own Chemists Own Decongestant Nasal Spray 18Ml Generic Of Drixine

Brand: CHEMIST OWN
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  • Chemists Own Decongestant Nasal Spray 18ml (Generic of DRIXINE)
  • Product Type: MEDICATION
  • Brand: CHEMIST OWN
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#10 Top Pick
Fess Nasal Defence Sinus Decongestant Saline Spray 30 ml

Fess Nasal Defence Sinus Decongestant Saline Spray 30 ml

Brand: Fess
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  • Helps guard against airborne bacteria
  • With vitamin E and tea tree oil
  • Helps relieve nasal and sinus congestion
  • Perfect for airborne infections, such as the common cold
  • Washes away pollutants
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