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Updated: 08 Oct 2025

10 Best Health Saline Nasal Spray

#1
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Xlear Natural Nasal Spray with Xylitol, 1.5 fl oz (Pack of 2)

Brand: Xlear
$36.99
⭐ 4.2
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    NATURAL SALINE SOLUTION & NASAL RINSE: Our nasal saline spray will gently clean and moisturize the sinus tissues. Our nose spray will help clean your nose from pollen, pollution, contaminants, and other irritants.
  • PLANT-SOURCED XYLITOL NASAL RINSE & SPRAY: Our natural nasal cleaner is the ideal daily sinus rinse that will open your airways. Using our saline nose spray before bed may reduce snoring.
  • IMPROVED FORMULA WITH XYLITOL: Our patented saline nasal spray solution naturally opens airways. Xylitol's powerful oral and upper respiratory benefits come from its unique five-carbon structure. Xylitol reduces contaminant adhesion on your nasal tissue.
  • EASY TO USE DIRECTIONS: Clear the nasal passageway by gently blowing your nose before using Xlear. Prime the pump by holding the sinus rinse bottle upright and pumping one or more times until the saline solution is dispensed. Insert nozzle into nostril and depress pump completely while breathing in through your nose. Spray each nostril 2-4 times and use at least twice daily.
  • WASH AWAY POLLUTANTS: Our natural saline nasal spray can wash away pollutants. Use our sinus spray daily to keep your nasal passages clean. Each 1.5 oz bottle delivers approx. 240 fine mist Sprays.
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#2
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Little Remedies Sterile Saline Nasal Mist | Safe for Newborns | 3 Fl Oz (Pack of 1) (50% More)

Brand: Little Remedies
$19.20 ($22.59 / 100
⭐ 4.4
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    Relieves runny, stuffy, dry, or crusty noses
  • Flushes and removes mucus from little noses to help little ones breathe easy; safely moisturizes
  • Safe for newborns; drug-free, no side effects
  • Use as often as necessary to keep baby's nose clear and moisturized
  • 3 Fl Oz (50% More)
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#3
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NeilMed Pharmaceuticals - PediaMist Saline Spray - 75 ml.

Brand: NeilMed
$12.49
⭐ 4.2
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    No features listed
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#4
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Xlear Natural Xylitol Saline Nasal Spray for Kids - Daily Nose Moisturizer, 0.75 fl oz (Pack of 1)

Brand: Xlear
$13.99 ($63.07 / 100
⭐ 4.1
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    NATURAL SALINE SOLUTION & NASAL RINSE: Our nasal saline spray will gently clean and moisturize the sinus tissues. Our nose spray will help clean your nose from pollen, pollution, contaminants and all other irritants.
  • KID SAFE NASAL RINSE & SPRAY: Our all natural nasal cleaner is safe for kids, drug-free, non-addictive, Non GMO Project Verified and is effective without the use of steroids, drugs or chemicals. Its the ideal daily sinus cleanser that will open your airways. Use our saline nose spray before bed may help reduce snoring.
  • IMPROVED FORMULA WITH XYLITOL: Our patented saline nasal spray solution naturally opens airways. Xylitol's powerful oral and upper respiratory benefits come from its unique five-carbon structure.
  • EASY TO USE DIRECTIONS: Clear the nasal passageway by gently blowing your nose before using Xlear. Prime the pump by holding the sinus rinse bottle upright and pumping one or more times until the saline solution is dispensed. Insert nozzle into nostril and depress pump completely while breathing in through your nose. Spray each nostril 2-4 times and use at least twice daily.
  • NATURAL NASAL SPRAY: Our natural saline nasal spray will wash away pollutants. Use our sinus spray daily to protect and keep your nasal passages clean. Each 0.75 fl oz bottle can also be used as drops for children.
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#5
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Fess Little Noses Saline Nose Spray 15 ml

Brand: Fess
$17.68 ($117.87 / 10
⭐ 4.6
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    A baby naturally breathes through their nose for the first few months
  • Helps to baby make feeding and sleeping easier
  • Non medicated so you can use it as often as needed, from the day your baby's born
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#6
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Fess Eucalyptus Nasal Spray 30 ml

Brand: Fess
$10.79 ($35.97 / 100
⭐ 4.8
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    A natural way to help relieve nasal congestion
  • Helps relieve nasal congestion caused by sinusitis, hayfever and colds
  • Helps clean and clear blocked noses
  • Washes away allergens, dust and pollen
  • With fresh aroma of eucalyptus
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#7
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Fess Little Noses Saline Nose + Aspirator Blocked Sinus Decongestant Spray 15 ml

Brand: Fess
$13.99
⭐ 4.1
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    A non-medicated saline nasal spray for the relief of nasal congestion
  • Keeps your baby's nose clear as a blocked nose can disrupt sleep, nursing and feeding
  • Helps to remove the nasal mucus so your baby can breathe easier, naturally
  • Helps maintain nasal health
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#8
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Neilmed Nasamist Saline Nasal Spray 75 ml

Brand: NeilMed
$14.40 ($19.20 / 100
⭐ 4.8
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    Sinus pressure and nasal congestion
  • Nasal symptoms from flu and cold
  • Nasal allergies and dryness
  • Nasal irritation from occupational
  • Spray to protect, cleanse, moisturize and soothe nasal passages
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#9
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Xlear Natural Nasal Spray with Xylitol, 1.5 fl oz (Pack of 1)

Brand: Xlear
$18.99 ($12.66 / Fl
⭐ 4.7
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    NATURAL SALINE SOLUTION & NASAL RINSE: Our nasal saline spray will gently clean and moisturize the sinus tissues. Our nose spray will help clean your nose from pollen, pollution, contaminants, and other irritants.
  • PLANT-SOURCED XYLITOL NASAL RINSE & SPRAY: Our natural nasal cleaner is the ideal daily sinus rinse that will open your airways. Using our saline nose spray before bed may reduce snoring.
  • IMPROVED FORMULA WITH XYLITOL: Our patented saline nasal spray solution naturally opens airways. Xylitol's powerful oral and upper respiratory benefits come from its unique five-carbon structure. Xylitol reduces contaminant adhesion on your nasal tissue.
  • EASY TO USE DIRECTIONS: Clear the nasal passageway by gently blowing your nose before using Xlear. Prime the pump by holding the sinus rinse bottle upright and pumping one or more times until the saline solution is dispensed. Insert nozzle into nostril and depress pump completely while breathing in through your nose. Spray each nostril 2-4 times and use at least twice daily.
  • WASH AWAY POLLUTANTS: Our natural saline nasal spray can wash away pollutants. Use our sinus spray daily to keep your nasal passages clean. Each 1.5 oz bottle delivers approx. 240 fine mist Sprays.
Check Price
#10
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Fess Saline Nasal Spray 30 ml

Brand: Fess
$6.00 ($20.00 / 100
⭐ 4.7
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    Helps relieve nasal congestion caused by sinusitis, hayfever and colds
  • Washes away allergens, dust and pollen
  • Helps clean and clear blocked noses
  • Helps maintain nasal health
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