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Updated: 08 Oct 2025

10 Best Hypoallergenic Pillowcases

#1
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THXSILK Silk Pillow Cases, 100% Mulberry Silk Pillowcase for Hair and Skin, 22 Momme Hypoallergenic Pillow Cover with Hidden Zipper, 1pc, (Dark Gray, Standard 20"x26")

Brand: THXSILK
$35.50
⭐ 4.1
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    100% MULBERRY SILK: THXSILK pillowcase is made of 100% long strand, Grade 6A+ Pure Mulberry Silk, which is smooth, soft and antistatic, maintains the balance of skin moisture. Compared with satin polyester, pure silk is a more organic fiber with relatively low carbon footprint, low soil and low land impact. It is composed of animal proteins and contains 53 kinds of Amino acids that are believed to effectively improve skin conditions.
  • BENEFITS FOR HAIR, SKIN AND SLEEP: A natural silk pillowcase allows your hair and skin to glide effortlessly along the surface of your pillow. Less friction helps reduce hair breakage and promotes skin smooth. Comfortable and breathable, pure mulberry silk is also a natural temperature regulator, which helps maintaining the correct body temperature. It keeps you feel cool in summer and warm in winter.
  • CONCEALED ZIPPER + DURABILITY: Concealed zipper design keeps the pillowcase seamless and uniform, prevents your pillow from moving around during the night and makes it easy to slip the pillow in and out for frustration-free washing. The pillowcase has exquisite craftsmanship of the neat stitches, and durable plain color which is not easy to fade after washing.
  • GREAT GIFT CHOICE: Carefully wrapped in a gift package, the silk pillowcase is an ideal present to be given to your loved ones for any holidays such as Valentine's Day, Thanksgiving, Christmas and New Year festivals, as well as special occasions like weddings, bridal and baby showers, birthdays, anniversaries. etc. We offer a wide range of colors and sizes to fit your taste. (Standard: 20"x26", Queen: 20"x30", King: 20"x36", California King: 20"x40")
  • WASHING INSTRUCTIONS: Hand-washing with cool water and dry clean are preferred. You can also put the pillowcase in a washing machine set to the gentle cycle, and we suggest to use a mesh wash bag when do so. Lay flat to dry. If you have any problem with the silk pillowcase, please feel free to contact us.
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#2
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Gioia Casa Bamboo Microfibre European Pillowcases - Breathable, Moisture-Wicking & Hypoallergenic for Cool Comfort - Linen - One Pair

Brand: Gioia Casa
$19.99
⭐ 4.8
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    LUXURIOUS 35% BAMBOO AND 65% MICROFIBRE BLEND FOR ULTIMATE COMFORT: These pillowcases are crafted from a premium blend of 35% bamboo and 65% microfibre, offering a smooth, soft texture that enhances your sleep experience with both comfort and durability.
  • TEMPERATURE-REGULATING AND BREATHABLE FABRIC: The bamboo fibres naturally regulate temperature, keeping you cool in warm weather and warm in cooler conditions. The breathable material promotes better airflow, ensuring a comfortable nights sleep in any season.
  • MOISTURE-WICKING PROPERTIES FOR A DRY, COMFORTABLE SLEEP: The bamboo fabric efficiently wicks away moisture, absorbing sweat and releasing it quickly. This ensures that you stay dry and comfortable throughout the night, especially during warmer months.
  • NATURALLY HYPOALLERGENIC AND SKIN-FRIENDLY: Ideal for allergy sufferers or those with sensitive skin, these pillowcases are hypoallergenic and resistant to dust mites and other allergens. The fabric is gentle on your skin, providing a clean, soothing sleep environment.
  • EASY CARE AND MACHINE WASHABLE: Designed for everyday use, these pillowcases are machine washable for quick and easy cleaning. They maintain their softness, color, and shape even after repeated washes, ensuring long-lasting use.
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#3
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Mulberry Satin Silk Pillowcase for Hair and Skin - Soft Breathable Smooth Both Sided Silk Pillow Cover Pair - Standard Size 50x75cm (White, Standard)

Brand: SANOOR
$17.98
⭐ 4.2
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    MULBERRY SATIN SILK - Dont settle for a Low quality synthetic imitation. Our soft, cooling, ultra-smooth satin silk is sourced from the best sources from tree. Experience the difference for yourself.
  • ENHANCE YOUR BEAUTY SLEEP: Sleeping on our hypoallergenic, non-irritating satin pillowcase can also help your skin. As the friction of your skin decreases, while you sleep, you will experience fewer sleep wrinkles, which is equivalent to fewer wrinkles over time.
  • ENVELOPE CLOSURE DESIGN: When you sleep, no zipper closure will poke your face. The satin pillowcase does not have a zipper closure but uses an envelope closure design. When you are resting, the silky pillowcase can hold your pillow firmly in place.
  • NATURAL MATERIAL: The pillow cover utilizes 100% polyester satin to provide a resilient feel with a distinctive and lustrous appearance, which gives it a smooth finish and double-sided use. The pillowcase is a natural material and a skin-friendly choice.
  • MULTIPLE COLORS: We have a variety of colors for you to choose from, from soft tones to bright tones, you will surely find a satin pillowcase that complements your decor. The outstanding and durable plain color will not fade easily after washing.Machine wash cold, gentle cycle, tumble dry at low temperature, cool iron if needed. Do not bleach.
  • BEST FOR HAIR & SKIN: Satin silk pillowcases can nourish the skin, increase the vitality of the skin's epidermis, and prevent skin aging. In addition, silk can keep your hair moisturized and healthy, and protect your hair from annoying tangles.
  • Enjoy Quality Sleep: The satin pillowcase will maintain its good appearance and quality sleep, making it a good decoration for your bedroom.
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#4
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CleverPolly Vintage Washed Microfibre European Pillowcases - Ultra Soft, Comfy, Hypoallergenic, Breathable Bed Pillowcases - Set of 2 Luxurious European Pillow Covers - Linen

Brand: CleverPolly
$19.95
⭐ 4.2
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    : Upgrade your sleep with CleverPolly's Vintage Washed Microfibre European Pillowcases. They're carefully made from 100% vintage-washed microfibre to redefine luxury, giving you a pure and extravagant experience like no other.
  • : CleverPolly put a lot of thought into making these pillowcases just right for all seasons. They're not too heavy or too light, so you can enjoy them all year long. Whether it's hot or cold outside, these pillowcases will keep you comfy.
  • : The CleverPolly Vintage Washed Microfibre European Pillowcases come in many different colors to easily fit your bedroom's look and make it look better. With so many color choices, you can easily improve how your bedroom looks.
  • : CleverPolly Vintage Washed Microfibre European Pillowcases make keeping things tidy a breeze. You can just toss them in the washing machine when needed. No more fussing with handwashing or complicated care instructions. It's a quick and easy way to ensure your pillowcases always look fresh and lovely, without spending much time or effort. So, say farewell to the tedious chores and savor the lasting charm of your bedding with ease.
  • : These pillowcases are designed to fit european size pillows, making them a versatile option for any bedroom. Whether you have a guest room, master bedroom, or kid's room, these pillowcases will fit perfectly on your pillows. Plus, their versatile size means you can easily switch up your bedding decor without having to worry about buying new pillows.
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#5
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Two-Sided 100% Mulberry Silk Hypoallergenic Pillowcase Slip Skin Face Hair Beauty Care Gift Box, Grade 6A (Pistachio)

Brand: Luxor Crown
$29.90
⭐ 4.2
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    Material: 100% Pure Mulberry Silk
  • Grade 6A: The highest and finest quality silk
  • Luxurious silky-smooth texture
  • Anti-static properties ensuring you wake up with shiny hair
  • Zipper Closure and Piped Edge
  • Hypoallergenic, breathable and chemical-free
  • Natural temperature-regulating properties
  • Hand wash or gentle cold-machine wash. Air dry only
  • 1 Piece
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#6
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Dreamaker Superfine Washed Microfibre European Pillowcase (65x65cm) - Stylish, Sage Green, Soft, Breathable and Hypo-Allergenic Pillow Cover

Brand: Dreamaker
$16.15
⭐ 4.2
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    Silky Smooth: Made with superfine washed microfibre for a luxurious feel against your face.
  • Versatile Styling: Suitable for standard and euro-sized pillows, and the rich colour range also comes in our microfibre quilt cover sets and sheet sets.
  • Fade-Resistant: Crafted to maintain its colour brilliance after multiple washes.
  • Envelope Closure: Keeps your pillow securely tucked in for a neat appearance.
  • Package Contents: Standard twin pack comes with two pillowcases, Euro size comes in a single, offering great value and convenience.
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#7
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Gioia Casa Luxury Pillowcase - Copper, 1pc - Soft Anti Wrinkle, Hypoallergenic, Washable Bed Pillowcases - 100% Pure Mulberry Silk on Both Sides

Brand: Gioia Casa
$39.99
⭐ 4.1
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    LUXURIOUS 100% MULBERRY SILK: Crafted with pure Mulberry silk on both sides, this pillowcase delivers an ultra-soft, smooth texture that pampers your skin and hair for a rejuvenating sleep experience.
  • SKIN & HAIR CARE ESSENTIAL: Reduces friction to help prevent wrinkles, hair breakage, and bedhead, ensuring you wake up with smoother skin and healthier-looking hair.
  • HYPOALLERGENIC & BREATHABLE: Naturally resistant to dust mites and allergens, this silk pillowcase is ideal for sensitive skin, promoting a clean and healthy sleep environment.
  • EASY CARE & DURABILITY: Machine washable for hassle-free maintenance, this pillowcase retains its luxurious look and feel even after repeated washes.
  • VIBRANT COLOR OPTIONS: Choose from a stunning palette, including Black, Champagne, Charcoal, Copper, Dark Purple, Emerald Green, Navy Blue, Pink, Red, Silver, Sky Blue, Sage Green, Teal, and White, to match any bedroom dcor beautifully.
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#8
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Niagara Sleep Solution Pillow Protectors Zippered Queen 20x30 Inches 4 Pack White Soft Hypoallergenic Brushed Microfiber Reduces Allergies Respiratory Irritation

Brand: Niagara Sleep Solution
$32.99
⭐ 4.6
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    Quality & Comfort-Our Microfiber pillow cases zippered standard Niagara Pillow protectors are non allergenic pillow covers. Plain weave pillow encasements ensures softness,smoothness and bed pillow protectors are allergenic pillow covers.
  • Resists Allergies & Respiratory Irritations :Set of 4 White Pillowcases : Pillow Cases are easy to use with strong zippper that resists allergies and reduces the respiratory irritaion , good for people suffering from allergies.
  • Pillow Covers :4 Pack pillowcases are cost effective solution for pillow protection.
  • Breathable Fabric -Our Pillow protector pillow encasements are made in all sizes Standard 20" x 26", Jumbo / Queen 20" x 30", King 20" x 36" to create soft, and breathable and enhanced protection. Pillow case protectors come in 4 pack style queen pillow case covers also serves as dust protector covers.
  • Fade & Stain Resistant: Our standard 4 pack pillow covers are dust protector covers are No PVC's, phthalates, vinyl or toxic chemicals ,moisture. Machine Washable and tumble dry low.
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#9
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Set of 2 Waterproof Pillow Protector, JOMWEN Quilted Zipped, Ultra-Soft & Machine Washable Pillow Protectors, Breathable Hypoallergenic and Noiseless, Comfortable, White (2, 50cm x 75cm)

Brand: JOMWEN
$24.99
⭐ 5
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    Advanced Waterproof ProtectionFeatures a diamond pattern stitching with microfiber filling, offering full waterproof protection to keep your pillows dry from spills, stains, and moisture
  • Ultra-Soft for Hotel-Quality ComfortMade from plush fabric, providing a luxurious, cloud-like feel for a cozy and restful nights sleep.
  • Breathable, Hypoallergenic & Secure FitPromotes airflow, regulates temperature, and features a fully zipped enclosure with an auto-locking zipper to ensure full coverage and peace of mind against allergens and liquids.
  • Quilted Padding for Extra CushioningAdds softness and support to your pillow, helping relieve pressure points for enhanced comfort.
  • Durable & Long-LastingProtects your pillows and helps extend their lifespan with a long-lasting, waterproof, and comfortable zippered cover, providing extra cushioning for restful sleep.
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#10
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Luxor Crown Set of 2 Mulberry Silk Standard Pillowcases (White)

Brand: LUXOR
$23.00
⭐ 4.4
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    Front Material : 100% Pure Mulberry Silk, Reverse Material : Non-Slip Polyester
  • Dimensions : 48x73 cm each pillowcase, Easy care with Hidden zipper
  • Highly delicate on the skin, Cool and soothing to the touch, Silk is the natural fibres allow your skin to breathe
  • Great gifts for mum, wife or girlfriend. The best gift choice for each festival, Christmas, birthday, anniversary etc
  • 100% Guarantee: Please feel free to contact us to get a FREE Replacement if there is any problem on our products. Welcome every customer contact us to give us some advice and suggestions, we will try our best to improve it
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