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Updated: 06 Apr 2026

10 Best Laxatives Suppository

#1 Best Pick
OsmoLax Relief Macrogol Osmotic Laxative Powder 35 Doses 595g

OsmoLax Relief Macrogol Osmotic Laxative Powder 35 Doses 595g

Brand: OsmoLax
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  • Provides effecive relief of consipation
  • Helps to restore the body's natural rhythm so you can get on with life
  • Has no salty taste so it can be mixed with any hot or cold drink
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#2 Best Value
Prunelax Laxative Extra Strength - 80 tablets- 15 mg. Natural Laxative Tablets - With Senna - Constipation Relief Tablets for Adults/Elderly

Prunelax Laxative Extra Strength - 80 tablets- 15 mg. Natural Laxative Tablets - With Senna - Constipation Relief Tablets for Adults/Elderly

Brand: Prunelax
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  • Effective Relief: Natural laxative tablets with Senna offer a reliable solution for occasional constipation by stimulating the bowel muscles to promote a gentle, predictable bowel movement.
  • Natural Ingredients: These laxative tablets are formulated with natural ingredients, primarily Senna leaf extract, known for its potent laxative properties.
  • Convenient and Easy to Use: The tablets are easy to incorporate into your daily routine. Simply take the recommended dosage with a glass of water before bedtime. Works in 8 to 12 hours.
  • Daily dosage: 1 to 2 tablets. Supports Digestive Health: In addition to providing relief from constipation, Senna has been traditionally used to support overall digestive health.
  • Travel-Friendly: Packaged in a compact and portable form, these laxative tablets are perfect for travel. They provide a convenient option to maintain digestive regularity on the go.
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#3 Budget Pick
Fleet Adult Glycerin Suppositories 50-Count (2-Pack)

Fleet Adult Glycerin Suppositories 50-Count (2-Pack)

Brand: Fleet Glycerin
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  • Each container comes with 50-Adult Suppositories. 2-Pack (100 Suppositories Total)
  • Fleet Adult Glycerin Suppositories promotes a bowel movement within 15 Minutes to 1 Hour.
  • Formulated with Aloe. A convenient alternative for those who prefer not to use liquid enemas.
  • Doctor-recommended glycerin works by attracting water into the stool to promote a bowel movement.
  • Before using Fleet Glycerin Suppositories, be sure to review the complete labeling.
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#4 Top Choice
Prunelax Laxative Extra Strength - 40 tablets - 15 mg. Natural Laxative Tablets - with Senna - Constipation Relief Tablets for Adults/Elderly

Prunelax Laxative Extra Strength - 40 tablets - 15 mg. Natural Laxative Tablets - with Senna - Constipation Relief Tablets for Adults/Elderly

Brand: Prunelax
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  • Effective Relief: Natural laxative tablets with Senna offer a reliable solution for occasional constipation by stimulating the bowel muscles to promote a gentle, predictable bowel movement.
  • Natural Ingredients: These laxative tablets are formulated with natural ingredients, primarily Senna leaf extract, known for its potent laxative properties.
  • Convenient and Easy to Use: The tablets are easy to incorporate into your daily routine. Simply take the recommended dosage with a glass of water before bedtime. Works in 8 to 12 hours.
  • Daily dosage: 1 to 2 tablets: Supports Digestive Health: In addition to providing relief from constipation, Senna has been traditionally used to support overall digestive health.
  • Travel-Friendly: Packaged in a compact and portable form, these laxative tablets are perfect for travel. They provide a convenient option to maintain digestive regularity on the go.
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#5 Popular Choice
Fleet Suppos Adult Size 24s Fleet Adult Glycerin Suppository Laxatives

Fleet Suppos Adult Size 24s Fleet Adult Glycerin Suppository Laxatives

Brand: C B Fleet
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  • TARGETED ACTION: Work directly in the lower colon, minimizing bothersome side effects like cramping or bloating
  • FAST-ACTING LAXATION: Glycerin draws water into the stool, softening it for easier passage and promoting a comfortable feeling of bowel movement
  • GENTLE ON YOUR SYSTEM: Free from harsh stimulants, making them ideal for those with sensitive stomachs or pregnant women under physician supervision
  • PRE-LUBRICATED FOR COMFORT: Designed with a smooth surface that ensures effortless insertion and minimizes discomfort
  • DISCREET AND PORTABLE: Compact and mess-free, it comes in a jar for discreet use anytime, anywhere; No mixing, no measuring
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#6 Top Pick
Dulcolax Bisacodyl 5mg Constipation Relief Gastro-Resistant Two Way Action to Stimulate Bowels and Soften Stools 20 Tablets

Dulcolax Bisacodyl 5mg Constipation Relief Gastro-Resistant Two Way Action to Stimulate Bowels and Soften Stools 20 Tablets

Brand: Dulcolax
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  • Contains 5mg bisacodyl for effective constipation relief
  • Stimulates bowel muscles to promote natural movements
  • Gentle, fast-acting and non-habit forming formula
  • Provides predictable relief for occasional constipation
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#7 Top Pick
Fleet Children's Pedia-Lax Liquid Glycerin Suppositories - 6 Suppositories

Fleet Children's Pedia-Lax Liquid Glycerin Suppositories - 6 Suppositories

Brand: Fleet
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  • Uniquely formulated for kids ages 2-5
  • Provides gentle relief in minutes
  • Predictable glycerin-based suppository won't upset your child's digestive system
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#8 Top Pick
Fleet Suppos Adult Size 24S Adult Glycerin Suppository Laxatives

Fleet Suppos Adult Size 24S Adult Glycerin Suppository Laxatives

Brand: Fleet
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#9 Top Pick
Fleet Glycerin Suppositories Adult Laxative Jar, 50 Each

Fleet Glycerin Suppositories Adult Laxative Jar, 50 Each

Brand: Fleet
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  • Fleet Laxative Glycerin Suppositories provide fast, effective relief from occasional constipation and irregularity in 15 minutes to 1 hour
  • Laxative glycerin suppository works with your body to help gently unblock your system by attracting water into the colon
  • Fleet suppositories' easy to use, lubricated gentle glide tips are uniquely cone-shaped and formulated with soothing aloe for easier insertion
  • Fleet Laxative Glycerin Suppositories are stimulant-free laxatives for constipation relief
  • Fleet is the number one doctor-recommended brand of enemas* and suppositories** *ProVoice Data 2/1/22 to 1/31/23; **IQVIA Survey, 5/1/23 to 4/30/24 and TABS, L52W thru 5/19/24
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#10 Top Pick
Dulcolax Suppositories 10mg - Constipation relief - Predictable, Fast Relief - Softens and Stimulates Stools, 10 Pack

Dulcolax Suppositories 10mg - Constipation relief - Predictable, Fast Relief - Softens and Stimulates Stools, 10 Pack

Brand: Dulcolax
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  • Dulcolax Suppositories provide fast relief from constipation by softening and stimulating stools
  • Fast acting: Produces a bowel movement within 20 - 45 minutes after use
  • Dulcolax Suppositories contain 10mg of bisacodyl, which stimulates the muscles in the bowel (intestine) and rectum to promote movement
  • The active ingredient in Dulcolax Suppositories stimulates the bowel to further relieve constipation
  • Always read the label and follow the directions for use
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