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Updated: 08 Oct 2025

10 Best Pain Relief Creams

#1
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Penetrex Pain Relief Therapy [2 Oz] Apply Penetrex Anywhere You Experience Pain, Discomfort, Tingling or Numbness (Back, Neck, Knee, Foot, Shoulder, etc.). Trusted by 2 Million+ Sufferers Since 2009

Brand: Penetrex
$30.79
⭐ 4.2
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    IMMEDIATE, LASTING, HEALING RELIEF: Penetrex is preferred by those dealing with inflammation related ailments & injuries because it works! If you're suffering from Arthritis, Back Pain, Carpal Tunnel Syndrome, Tennis Elbow, Golf Elbow, Tendonitis, Bursitis, Sciatica, Neck Pain, Shoulder Pain, Hip Pain, Shin Splints, Neuropathy, Fibromyalgia, Plantar Fasciitis, Heel Pain, Chronic Pain, etc.
  • 100% -BACK : Your Penetrex Purchase & Complete Satisfaction is Personally & Unconditionally by Pamela Weiss, the Vice-President of Biomax Health Products. If you are less than 100% Satisfied with Penetrex, for ANY reason, we sincerely urge you to take advantage of her inchNo-Hassleinch, inchNo Questions Askedinch, inchNo Time Limitinch Policy. Penetrex Really Works!
  • MILLIONS OF CLIENTS WORLDWIDE: Sufferers in over 100 countries have now discovered this breakthrough formulation. With its greaseless, stainless and vanishing scent, reformulated Penetrex provides boosted potency of proven ingredients including Vitamin B6, Pyridoxine, Arnica, MSM, Cetyl Myristoleate, Choline Bitartrate, Glucosamine, Boswellia Serrata.
  • OFTEN IMITATED...NEVER DUPLICATED. Biomax applied for and was granted by The U.S. Patent Office Provisional Patent Status {#62397648} for its Invention known as the inchManifold Compound Emulsification Processinch. This breakthrough system pertains to the creation of not just the proprietary ingredient blend but the specific manufacturing process that results in the unique formulation
  • YOUR PRE/POST WORKOUT SOLUTION: Clients report particularly positive results for muscle & joint soreness and discomfort. Yoga & CrossFit practitioners as well as many other active lifestyle Professionals have found Penetrex extremely Effective & Restorative. Penetrex is recommended for use on its own or in conjunction with braces, splints, gloves, ultrasound treatment, physical therapy & massage.
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#2
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Dencorub Arthritis Cream, 100g

Brand: Dencorub
$6.70
⭐ 4.1
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    ALWAYS READ THE LABEL AND FOLLOW THE DIRECTONS FOR USE
  • Fast absorbing
  • No heat and no odor formulation
  • Non-staining and non-greasy
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#3
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Pain Away Forte+ Ultra Pro Joint and Muscle Pain Relief Cream 70g. Relief for symptoms of mild arthritis, bruising, mild joint and muscle pain and soreness with the power of Arnica, Australia's No. 1 Topical Anti-inflammatory Brand containing Arnica

Brand: Pain Away
$28.56
⭐ 4.4
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    Non-greasy texture absorbs rapidly into the skin
  • Designed for pinpoint application on specific areas
  • Ideal for individuals leading active lifestyles
  • Reduces inflammation to alleviate pain symptoms
  • Effective for temporary relief of arthritis discomfort
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#4
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Dencorub Dual Action, 100g

Brand: Dencorub
$4.69
⭐ 4.1
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    Dual Action 2 in 1 treatment
  • Non-greasy and absorbs quickly
  • Goes on feeling cold to ease pain, then heats for soothing relief
  • 100g cream tube
  • Heats up for soothing relief and absorbs quickly
  • ALWAYS READ THE LABEL AND FOLLOW THE DIRECTONS FOR USE
  • Active ingredients: METHYL SALICYLATE 150mg/g (15%), MENTHOL 30mg/g (3%), CAMPHOR 30mg/g (3%), EUCALYPTUS OIL 15mg/g (15%)
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#5
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Fisiocrem Solugel 250g – Muscle Pain Relief Gel with Naturally Derived Active Ingredients of Arnica, Calendula, Hypericum, Melalecua & Menthol, Soothes Sprains, Strains & Sore Muscles, Non-Greasy, Easily Absorbed

Brand: FISIOCREM
$29.49 ($11.80 / 100
⭐ 5
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    MUSCLE RELIEF SUPPORT: Helps provide temporary relief from muscle soreness caused by sprains, strains, or exercise recovery
  • EASILY ABSORBED FORMULA: Lightweight gel absorbs easily without leaving a sticky residue; suitable for on-the-go use
  • VERSATILE APPLICATION: Ideal for post-workout discomfort, general muscle tension, or sports-related soreness; suitable for active lifestyles
  • NATURALLY DERIVED ACTIVE INGREDIENTS & MENTHOL: Contains arnica, calendula, menthol, melaleuca, and hypericum.
  • NON-GREASY TEXTURE: Smooth and easy to apply; leaves no greasy feelperfect for daily use at home or in your gym bag
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#6
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Soodox Original Pain Relief Cream, Made in Australia with 100% Natural Active Ingredients, for relief from mild: Arthritis, Muscle Soreness and Stiffness, Muscular Pain and Joint Pain

Brand: Soodox
$21.95
⭐ 4.8
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    100% AUSTRALIAN MADE - Soodox Active Pain Relief Cream has a patented roll-on massage applicator, meaning you can relive your aches and pains and have no messy hands!
  • 100% NATURAL ACTIVE INGREDIENTS - Synergistic blend of 100% natural active ingredients work to reduce pains and increase blood circulation to the area in a formulation that enhances penetration to the area
  • TEMPORARY RELIEF FROM: Arthritis pain, muscle soreness and stiffness, muscular and joint pain, rheumatic pain
  • BENEFITS - Heat free, quickly absorbed cream that is non-oily and lightly fragranced
  • Soodox Original Pain Relief Cream can be used on active muscles before, during and after sport and exercise, or as part of a warm up routing to help revive muscle soreness and stiffness
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#7
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Pain Away Forte+ Joint and Muscle Pain Relief Cream 70 g

Brand: Pain Away
$24.52 ($35.03 / 100
⭐ 5
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    Non-greasy cream that absorbs quickly
  • Soothes with a refreshing menthol sensation
  • Promotes flexibility and mobility
  • Offers long-lasting relief for sustained comfort
  • Restores comfort and enhances well-being
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#8
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Neuropathy Nerve Pain Relief Cream - Maximum Strength Relief Cream for Foot, Hands, Legs, Toes Includes Arnica, Vitamin B6, Aloe Vera, MSM - Scientifically Developed for Effective Relief 2oz

Brand: Pharmapulse
$64.00
⭐ 4.7
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    FAST NEUROPATHY RELIEF: Works within minutes of application. Pure Sciences unique formula helps to reduce muscle, back, knee, elbow & arthritis pain, soothe stiffness and inflammation, relieve joint pain, fibromyalgia & carpal tunnel pain and pain in damaged nerves.
  • CONCENTRATED FORMULA: Pure Sciences Neuropathy is made up of powerful and potent superior clinically-proven ingredients, which means you don't need much balm to get maximum, lasting relief. Thanks to its effectiveness. One jar of Pure Sciences Neuropathy Pain Relief Cream will last you much longer.
  • SUPERIOR ABSORPTION: Absorbs quickly to provide targeted pain relief to your back, neck, knee, hip, shoulders, elbows, joints and muscles. Helps with skin conditions & supports the bodys natural healing processes.
  • SCIENTIFICALLY DEVELOPED: Expertly established formula penetrates deep. A little goes a long way. Great Value!
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#9
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Zea Relief Kunzea Pain Relief Cream, 50 g – Natural Anti-Inflammatory Formula for Muscle, Joint & Nerve Pain – Enriched with Vitamin E, Rosemary & Tasmanian Lavender – Sore Muscle & Arthritis Relief

Brand: Zea Relief
$27.44
⭐ 4.1
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    Natural Pain Relief: A powerful pain relief cream formulated with Kunzea, Rosemary, and Tasmanian Lavender to help reduce joint pain relief, muscle soreness, and inflammation naturally
  • Fast-Absorbing & Effective: This anti-inflammatory cream penetrates quickly through the skin, providing targeted relief for arthritis, mild nerve pain, muscle aches, strains, and inflammation
  • Skin-Soothing Enriched Formula: Infused with Vitamin E, cocoa butter, and shea butter to nourish and soothe the skin, improving skin health while helping to relieve pain and inflammation
  • Family-Friendly & Non-Toxic: Suitable for use by the whole family, this sore muscle treatment is safe, non-toxic, and ideal for those with chronic conditions like mild arthritis
  • Support Muscle Recovery: This muscle recovery cream not only helps manage pain but also boosts skin health, making it perfect for both post-workout relief and everyday use
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#10
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Zea Relief Kunzea Pain Relief Cream, 100 g – Natural Anti-Inflammatory Formula for Muscle, Joint & Nerve Pain – Enriched with Vitamin E, Rosemary & Tasmanian Lavender – Sore Muscle & Arthritis Relief

Brand: Zea Relief
$34.49
⭐ 4.4
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    Natural Pain Relief: A powerful pain relief cream formulated with Kunzea, Rosemary, and Tasmanian Lavender to help reduce joint pain relief, muscle soreness, and inflammation naturally
  • Fast-Absorbing & Effective: This anti-inflammatory cream penetrates quickly through the skin, providing targeted relief for arthritis, mild nerve pain, muscle aches, strains, and inflammation
  • Skin-Soothing Enriched Formula: Infused with Vitamin E, cocoa butter, and shea butter to nourish and soothe the skin, improving skin health while helping to relieve pain and inflammation
  • Family-Friendly & Non-Toxic: Suitable for use by the whole family, this sore muscle treatment is safe, non-toxic, and ideal for those with chronic conditions like mild arthritis
  • Support Muscle Recovery: This muscle recovery cream not only helps manage pain but also boosts skin health, making it perfect for both post-workout relief and everyday use
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