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Updated: 06 Apr 2026

10 Best Pillowcases Hypoallergenic

#1 Best Pick
THXSILK 100% Mulberry Silk Pillowcase for Hair and Skin Heath, Best Gift Choice, Grade 6A Silk Both Sides, Hypoallergenic Pillow Cover with Zipper, 1pc (King 20"x36", Emerald Green)

THXSILK 100% Mulberry Silk Pillowcase for Hair and Skin Heath, Best Gift Choice, Grade 6A Silk Both Sides, Hypoallergenic Pillow Cover with Zipper, 1pc (King 20"x36", Emerald Green)

Brand: THXSILK
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  • 100% MULBERRY SILK: THXSILK pillowcase is made of 100% long strand, Grade 6A+ Pure Mulberry Silk, which is smooth, soft and antistatic, maintains the balance of skin moisture. Compared with satin polyester, pure silk is a more organic fiber with relatively low carbon footprint, low soil and low land impact. It is composed of animal proteins and contains 18 kinds of Amino acids that are believed to effectively improve skin conditions.
  • BENEFITS FOR HAIR, SKIN AND SLEEP: A natural silk pillowcase allows your hair and skin to glide effortlessly along the surface of your pillow. Less friction helps reduce hair breakage and promotes skin smooth. Comfortable and breathable, pure mulberry silk is also a natural temperature regulator, which helps maintaining the correct body temperature. It keeps you feel cool in summer and warm in winter.
  • CONCEALED ZIPPER + DURABILITY: Concealed zipper design keeps the pillowcase seamless and uniform, prevents your pillow from moving around during the night and makes it easy to slip the pillow in and out for frustration-free washing. The pillowcase has exquisite craftsmanship of the neat stitches, and durable plain color which is not easy to fade after washing.
  • GREAT GIFT CHOICE: Carefully wrapped in a gift package, the silk pillowcase is an ideal present to be given to your loved ones for any holidays such as Valentine's Day, Thanksgiving, Christmas and New Year festivals, as well as special occasions like weddings, bridal and baby showers, birthdays, anniversaries. etc. We offer a wide range of colors and sizes to fit your taste. (Standard: 20"x26", Queen: 20"x30", King: 20"x36", California King: 20"x40")
  • WASHING INSTRUCTIONS: Hand-washing with cool water and dry clean are preferred. You can also put the pillowcase in a washing machine set to the gentle cycle, and we suggest to use a mesh wash bag when do so. Lay flat to dry. If you have any problem with the silk pillowcase, please feel free to contact us.
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#2 Best Value
PETTI Artigiani Italiani - Set of 2 Bed Pillowcases 45 x 45 cm, Plain Cushion Covers, Lilac, Pillowcase 100% Hypoallergenic Microfiber, Made in Italy

PETTI Artigiani Italiani - Set of 2 Bed Pillowcases 45 x 45 cm, Plain Cushion Covers, Lilac, Pillowcase 100% Hypoallergenic Microfiber, Made in Italy

Brand: PETTI Artigiani Italiani
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  • Directly from the catalog of PETTI Italian artisans, here is the set of 2 plain pillowcases made of 100% hypoallergenic microfibre.
  • A product specially designed and tailor-made to offer you the best experience in terms of quality, beauty, strength and softness.
  • Thanks to the selection of the best hypoallergenic microfibre fibres, our pillowcases are both durable, soft and delicate, perfect for pampering you during your best dreams.
  • Our pillowcases are 100% made in Italy and contain only natural and non-toxic products, which ensures that they are free of substances harmful to your health.
  • The set includes 2 pillowcases measuring 45 x 45 cm.
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#3 Budget Pick
ZIMASILK 100% Pure Mulberry Silk Pillowcase for Hair and Skin Health,Soft and Smooth,Both Sides Premium Grade 6A Silk,600 Thread Count,with Hidden Zipper,1pc (Queen 20''x30'',Peacock Blue)

ZIMASILK 100% Pure Mulberry Silk Pillowcase for Hair and Skin Health,Soft and Smooth,Both Sides Premium Grade 6A Silk,600 Thread Count,with Hidden Zipper,1pc (Queen 20''x30'',Peacock Blue)

Brand: ZIMASILK
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  • âś… 100% Mulberry Silk: Bringing you the best silk pillowcase means the highest grade 6A organic silk (Tips: Avoid cheaply silk pillowcases, they maybe Low Silk Content or Fake Silk). Also compare with some other brands, they mark their pillowcases as 21, 22 Momme. Zima silk pillowcase has same thickness. Both sides of Zima silk pillow case is constructed from 100% 19 momme Grade 6A mulberry silk.
  • âś… Only Real Mulberry Silk - The Perfect Sleep Fabric: Silk has been clinically proven to be the fabric of choice for those skin conscious. Satin and other imitations are harsh on the skin and hair, causing wrinkles, knotted and tangled hair, as well as skin irritation. A completely natural and hypoallergenic silk pillowcase designed by our team of experts that does wonders for your hair, skin and overall health while you sleep.
  • âś… Silk Benefits for Hair and Skin: Zima silk pillowcases are made of pure mulberry silk. It has various kinds of Amino Acids that are believed to effectively stimulate your skin cells' metabolism. Silk is gentle and naturally nourishing on your hair and skin. Best for sensitive skin or minimizing morning lines, wrinkles, acne. Silk is anti static and friction, excellent for curly hair, bed head, hair breakage and hair loss.
  • âś… The High Quality and Durability: Superior durable plain color, not easy to fade after washing. Exquisite craftsmanship of the neat stitches. And there are more than 35 colors for your choice, ideal gift choice for Thanksgiving, Christmas, New Year festivals.
  • âś… 180 Days Guarantee: Experience the luxury of Zima silk pillow cases. We believe that you will love this silk cover as we do. If there is any quality issues, we offer a 180 days guarantee, please feel free to contact us, we will make it right for you within 24 hours. We ensure you risk-free to shop from ZIMASILK
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#4 Top Choice
Luxor Crown Set of 2 Mulberry Silk Standard Pillowcases (White)

Luxor Crown Set of 2 Mulberry Silk Standard Pillowcases (White)

Brand: LUXOR
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  • Front Material : 100% Pure Mulberry Silk, Reverse Material : Non-Slip Polyester
  • Dimensions : 48x73 cm each pillowcase, Easy care with Hidden zipper
  • Highly delicate on the skin, Cool and soothing to the touch, Silk is the natural fibres allow your skin to breathe
  • Great gifts for mum, wife or girlfriend. The best gift choice for each festival, Christmas, birthday, anniversary etc
  • 100% Guarantee: Please feel free to contact us to get a FREE Replacement if there is any problem on our products. Welcome every customer contact us to give us some advice and suggestions, we will try our best to improve it
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#5 Popular Choice
Two-Sided 100% Mulberry Silk Hypoallergenic Pillowcase Slip Skin Face Hair Beauty Care Gift Box, Grade 6A (Emerald)

Two-Sided 100% Mulberry Silk Hypoallergenic Pillowcase Slip Skin Face Hair Beauty Care Gift Box, Grade 6A (Emerald)

Brand: Luxor Crown
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  • Material: 100% Pure Mulberry Silk
  • Grade 6A: The highest and finest quality silk
  • Luxurious silky-smooth texture
  • Anti-static properties ensuring you wake up with shiny hair
  • Zipper Closure and Piped Edge
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#6 Top Pick
100% Mulberry Silk Pillowcase for Hair and Skin, 25 Momme Pure Silk Pillow Case with Hidden Zipper, Both Sides Natural Silk Pillow Cover for Women Men 1pc (White)

100% Mulberry Silk Pillowcase for Hair and Skin, 25 Momme Pure Silk Pillow Case with Hidden Zipper, Both Sides Natural Silk Pillow Cover for Women Men 1pc (White)

Brand: Anicika
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  • Crafted in Silk, Designed for You: Do you often wake up with dry skin and tangle hair? It's time to get a pillowcase that Made from 100% pure mulberry silk(25 Momme), double siedes 6A grade natrual silk,conforming to the most rigorous standards from OEKO,Double-sided silk for maximum comfort and functionality—both sides offer the same skincare and hair care benefits .
  • Gentle on Skin, Kind to Hair: A natural silk pillowcase allows your hair and skin to glide effortlessly along the surface of your pillow. The silky surface of the pillowcase helps reduce friction and tension on the skin and hair, minimizing the wrinkles, creases, and hair breakage.Wake up with smoother skin, softer hair, and no more “bedhead”.
  • Hidden Zipper Design: Mulberry silk pillowcase(Queen Size 20"x30") with hidden zipper to prevent pillows from slipping out during sleep.Where Comfort Meets Elegance, Silk Pillowcase and add a touch of elegance to your bedroom decor, enhancing the overall aesthetic appeal of your sleeping space.
  • Care and Maintenance : Hand wash or gentle machine Wash pure silk pillow case. Use cold water and mild detergent (avoid bleach or harsh chemicals) . We suggest using a mesh wash bag when do so. Air-dry or tumble dry on low heat.Avoid wringing to prevent damage .
  • The Perfect Luxe Gift for Any Occasion: Are you looking for a thoughtful, indulgent gift? This real silk pillowcase is a luxurious treat for wives, mothers, sisters, and friends; Long-haired or curly-haired loved ones; Beauty lovers and self-care enthusiasts;Anyone who values a good night’s sleep.Available in a range of elegant, colors, it’s ideal for Christmas, birthdays, anniversaries, Mother’s Day, or give the gift of glowing skin and gorgeous hair.
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#7 Top Pick
Gioia Casa Luxury Pillowcase - 100% Pure Mulberry Silk on Both Sides - Soft Anti Wrinkle, Hypoallergenic, Washable Bed Pillowcases - Premium Pillow Cover That Protects Your Hair and Skin - Navy

Gioia Casa Luxury Pillowcase - 100% Pure Mulberry Silk on Both Sides - Soft Anti Wrinkle, Hypoallergenic, Washable Bed Pillowcases - Premium Pillow Cover That Protects Your Hair and Skin - Navy

Brand: Gioia Casa
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  • LUXURIOUS 100% MULBERRY SILK: Crafted with pure Mulberry silk on both sides, this pillowcase offers a silky-smooth texture that feels incredibly soft and gentle against the skin.
  • ANTI-WRINKLE & SKIN-FRIENDLY: Designed to reduce friction, this silk pillowcase helps prevent facial wrinkles, hair breakage, and bedhead, ensuring you wake up refreshed and flawless.
  • HYPOALLERGENIC & BREATHABLE: Naturally hypoallergenic and resistant to dust mites, Mulberry silk is ideal for sensitive skin and promotes a clean, healthy sleeping environment.
  • DURABLE & EASY TO CARE FOR: This premium pillowcase is machine washable and retains its luxurious look and feel over time, making it perfect for everyday use.
  • STYLISH COLOR OPTIONS: Available in stunning colors including Dark Purple, Charcoal, Silver, Black, White, Pink, Navy, Champagne, and Red, this pillowcase adds elegance to any bedroom dĂ©cor.
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#8 Top Pick
Gioia Casa Luxury Pillowcase - 100% Pure Mulberry Silk on Both Sides - Soft Anti Wrinkle, Hypoallergenic, Washable Bed Pillowcases - Premium Pillow Cover That Protects Your Hair and Skin - Black

Gioia Casa Luxury Pillowcase - 100% Pure Mulberry Silk on Both Sides - Soft Anti Wrinkle, Hypoallergenic, Washable Bed Pillowcases - Premium Pillow Cover That Protects Your Hair and Skin - Black

Brand: Gioia Casa
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  • LUXURIOUS 100% MULBERRY SILK: Crafted with pure Mulberry silk on both sides, this pillowcase offers a silky-smooth texture that feels incredibly soft and gentle against the skin.
  • ANTI-WRINKLE & SKIN-FRIENDLY: Designed to reduce friction, this silk pillowcase helps prevent facial wrinkles, hair breakage, and bedhead, ensuring you wake up refreshed and flawless.
  • HYPOALLERGENIC & BREATHABLE: Naturally hypoallergenic and resistant to dust mites, Mulberry silk is ideal for sensitive skin and promotes a clean, healthy sleeping environment.
  • DURABLE & EASY TO CARE FOR: This premium pillowcase is machine washable and retains its luxurious look and feel over time, making it perfect for everyday use.
  • STYLISH COLOR OPTIONS: Available in stunning colors including Dark Purple, Charcoal, Silver, Black, White, Pink, Navy, Champagne, and Red, this pillowcase adds elegance to any bedroom dĂ©cor.
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#9 Top Pick
Two-Sided 100% Mulberry Silk Hypoallergenic Pillowcase Slip Skin Face Hair Beauty Care Gift Box, Grade 6A (Grey)

Two-Sided 100% Mulberry Silk Hypoallergenic Pillowcase Slip Skin Face Hair Beauty Care Gift Box, Grade 6A (Grey)

Brand: Luxor Crown
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  • Material: 100% Pure Mulberry Silk
  • Grade 6A: The highest and finest quality silk
  • Luxurious silky-smooth texture
  • Anti-static properties ensuring you wake up with shiny hair
  • Zipper Closure and Piped Edge
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#10 Top Pick
Two-Sided 100% Mulberry Silk Hypoallergenic Pillowcase Slip Skin Face Hair Beauty Care Gift Box, Grade 6A (Purple)

Two-Sided 100% Mulberry Silk Hypoallergenic Pillowcase Slip Skin Face Hair Beauty Care Gift Box, Grade 6A (Purple)

Brand: Luxor Crown
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  • Material: 100% Pure Mulberry Silk
  • Grade 6A: The highest and finest quality silk
  • Luxurious silky-smooth texture
  • Anti-static properties ensuring you wake up with shiny hair
  • Zipper Closure and Piped Edge
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